MCMedicalCodingSoftware
M35.9

M35.9: Systemic involvement of connective tissue, unspecified

Billable / specific codeICD-10-CM

M35.9 is a billable, specific ICD-10-CM code for systemic involvement of connective tissue, unspecified. It is valid for submission on a claim.

Check M35.9 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Autoimmune disease (systemic) NOS
  • Collagen (vascular) disease NOS

Excludes1 inherited from the categories above M35.9

A category’s note binds every code beneath it.

Written on M35: Other systemic involvement of connective tissue

  • reactive perforating collagenosis (L87.1)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

M35.9 is named in 10 Medicare coverage policies: 3 listing it as supporting medical necessity, and 7 listing it as NOT covered. Which one applies depends on your Medicare contractor.

  • A58865Billing and Coding: Amniotic and Placental-Derived Product Injections and/or Applications for Musculoskeletal Indications, Non-Woundnot covered
  • A58883Billing and Coding: Amniotic and Placental-Derived Product Injections and/or Applications for Musculoskeletal Indications, Non-Woundnot covered
  • A58893Billing and Coding: Amniotic and Placental-Derived Product Injections and/or Applications for Musculoskeletal Indications, Non-Woundnot covered
  • A59374Billing and Coding: Amniotic and Placental-Derived Product Injections and/or Applications for Musculoskeletal Indications, Non-Woundnot covered

Alphabetic index entries that lead here

  • Collagenosis, collagen disease(nonvascular) (vascular)
  • Dyscollagenosis
  • Ataxia, ataxy, ataxic›gluten
  • Autoimmune›disease(systemic)
  • Disease, diseased›autoimmune NOS(systemic)
  • Disease, diseased›collagen NOS(nonvascular) (vascular)
  • Disease, diseased›connective tissue, systemic(diffuse)
  • Disease, diseased›mesenchymal
  • Skin›hidebound
  • Syndrome›connective tissue
  • Polyneuropathy›in›collagen vascular disease NEC
  • Polyneuropathy›in›systemic›connective tissue disorder

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under M35

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.