Z92.22
Z92.22: Personal history of monoclonal drug therapy
Billable / specific codeICD-10-CMPOA exempt
Z92.22 is a billable, specific ICD-10-CM code for personal history of monoclonal drug therapy. It is valid for submission on a claim.
Check Z92.22 with the rest of the claim: free scrubberExcludes2: not included here, but may coexist
The excluded condition is not part of this code, but a patient can have both. You may code both.
- personal history of immune checkpoint inhibitor therapy (Z92.26)
Risk adjustment
No CMS-HCC V28 category: this code does not change a RAF score.
Medicare coverage
Z92.22 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.
- A56907Billing and Coding: Bisphosphonate Drug Therapy
- A57189Billing and Coding: Serum Magnesium
- A59561Billing and Coding: Bisphosphonate Drug Therapy
Alphabetic index entries that lead here
- History›personal›drug therapy›monoclonal drug
Code history
Unchanged in every release from FY2024 to FY2027.