MCMedicalCodingSoftware
Z92.21

Z92.21: Personal history of antineoplastic chemotherapy

Billable / specific codeICD-10-CMPOA exempt

Z92.21 is a billable, specific ICD-10-CM code for personal history of antineoplastic chemotherapy. It is valid for submission on a claim.

Check Z92.21 with the rest of the claim: free scrubber

Excludes2 inherited from the categories above Z92.21

Not part of this code, but both may be coded when both are present.

Written on Z92.2: Personal history of drug therapy

  • long term (current) drug therapy (Z79.-)

Written on Z92: Personal history of medical treatment

  • postprocedural states (Z98.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

Z92.21 is named in 2 Medicare coverage policies: 2 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56779Billing and Coding: Intravenous Immune Globulin
  • A57189Billing and Coding: Serum Magnesium

Alphabetic index entries that lead here

  • History›personal›chemotherapy for neoplastic condition
  • History›personal›drug therapy›antineoplastic chemotherapy

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under Z92.2

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.