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Z77.21

Z77.21Contact with and (suspected) exposure to potentially hazardous body fluids

Billable / specific codeICD-10-CM

Z77.21 is a billable, specific ICD-10-CM code for contact with and (suspected) exposure to potentially hazardous body fluids. It is valid for submission on a claim.

Excludes2 inherited from the categories above Z77.21

Also inherited, and the opposite of Excludes1: these conditions are not part of Z77.21, but a patient can have both, so you may code both.

Written on Z77 Other contact with and (suspected) exposures hazardous to health

  • contact with and (suspected) exposure to communicable diseases (Z20.-)
  • exposure to (parental) (environmental) tobacco smoke in the perinatal period (P96.81)
  • newborn affected by noxious substances transmitted via placenta or breast milk (P04.-)
  • occupational exposure to risk factors (Z57.-)
  • retained foreign body (Z18.-)
  • retained foreign body fully removed (Z87.821)
  • toxic effects of substances chiefly nonmedicinal as to source (T51-T65)

Other codes that can never be billed with Z77.21

These codes carry an Excludes1 note pointing at Z77.21. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading Z77.21 alone.

  • Z13.88Encounter for screening for disorder due to exposure to contaminants
  • Z03Encounter for medical observation for suspected diseases and conditions ruled out

Risk adjustment

Z77.21 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How Z77.21 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to Z77.21.

  • Contactbody fluids(potentially hazardous)
  • Exposurebody fluids(potentially hazardous)

Code history

Z77.21 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share Z77.2. If Z77.21 is not quite right, the correct code is usually one of these.

Questions about Z77.21

Is Z77.21 a billable ICD-10-CM code?
Yes. Z77.21 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does Z77.21 sit in the tabular list?
Factors influencing health status and contact with health services (Z00-Z99), in the block Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.