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Z15.89

Z15.89: Genetic susceptibility to other disease

Billable / specific codeICD-10-CMPOA exempt

Z15.89 is a billable, specific ICD-10-CM code for genetic susceptibility to other disease. It is valid for submission on a claim.

Check Z15.89 with the rest of the claim: free scrubber

Excludes1 inherited from the categories above Z15.89

A category’s note binds every code beneath it.

Written on Z15: Genetic susceptibility to disease

  • chromosomal anomalies (Q90-Q99)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Alphabetic index entries that lead here

  • Susceptibility to disease, genetic
  • Genetic›susceptibility to disease NEC

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under Z15.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.