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R78.81

R78.81: Bacteremia

Billable / specific codeICD-10-CM

R78.81 is a billable, specific ICD-10-CM code for bacteremia. It is valid for submission on a claim.

Check R78.81 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • sepsis-code to specified infection

Excludes2 inherited from the categories above R78.81

Not part of this code, but both may be coded when both are present.

Written on R78: Findings of drugs and other substances, not normally found in blood

  • mental or behavioral disorders due to psychoactive substance use (F10-F19)

Other codes that can never be billed with R78.81

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • A41Other sepsis
  • A49.9Bacterial infection, unspecified

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

R78.81 is named in 13 Medicare coverage policies: 13 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A52868Billing and Coding: Transesophageal Echocardiography (TEE)
  • A56505Billing and Coding: Transesophageal Echocardiography (TEE)
  • A56625Billing and Coding: Echocardiography
  • A56718Billing and Coding: Intravenous Immunoglobulin (IVIG)

Alphabetic index entries that lead here

  • Bacteremia
  • Findings, abnormal, inconclusive, without diagnosis›culture›blood
  • Positive›culture›blood

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under R78.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.