MCMCB Pro
R78

R78Findings of drugs and other substances, not normally found in blood

Non-billable headerICD-10-CM

R78 is a non-billable header ICD-10-CM code for findings of drugs and other substances, not normally found in blood. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes2 — not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • mental or behavioral disorders due to psychoactive substance use (F10-F19)

Use additional code

Add a secondary code to capture the detail described below.

  • code to identify the any retained foreign body, if applicable (Z18.-)

Other codes that can never be billed with R78

These codes carry an Excludes1 note pointing at R78. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading R78 alone.

  • R79.0Abnormal level of blood mineral
  • A41Other sepsis
  • A49.9Bacterial infection, unspecified

Risk adjustment

R78 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead R78

10 child codes. Green means billable.

Questions about R78

Is R78 a billable ICD-10-CM code?
No. R78 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does R78 sit in the tabular list?
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99), in the block Abnormal findings on examination of blood, without diagnosis (R70-R79).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.