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R65

R65: Symptoms and signs specifically associated with systemic inflammation and infection

Non-billable headerICD-10-CM

R65 is a non-billable header ICD-10-CM code for symptoms and signs specifically associated with systemic inflammation and infection. It cannot be billed on its own: choose one of the more specific child codes below.

Other codes that can never be billed with R65

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • R65.1Systemic inflammatory response syndrome (SIRS) of non-infectious origin
  • T79.4Traumatic shock
  • T79.4XXATraumatic shock, initial encounter
  • T79.4XXDTraumatic shock, subsequent encounter
  • T79.4XXSTraumatic shock, sequela

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

The condition this code belongs to

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead R65

2 child codes. Green means billable.

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.