Is R59.1 a billable ICD-10-CM code?

Yes. R59.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does R59.1 sit in the tabular list?

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99), in the block General symptoms and signs (R50-R69).

What cannot be coded together with R59.1?

R59.1 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above R59.1 (R59) and apply to it just the same.

R59.1

R59.1 — Generalized enlarged lymph nodes

Billable / specific codeICD-10-CM

R59.1 is a billable, specific ICD-10-CM code for generalized enlarged lymph nodes. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Lymphadenopathy NOS

Excludes1 inherited from the categories above R59.1

These are not written on R59.1, but they bind it: a note on a category applies to every code beneath it. Billing R59.1 with anything listed here is a denial.

Written on R59 — Enlarged lymph nodes

lymphadenitis NOS (I88.9)
acute lymphadenitis (L04.-)
chronic lymphadenitis (I88.1)
mesenteric (acute) (chronic) lymphadenitis (I88.0)

Other codes that can never be billed with R59.1

These codes carry an Excludes1 note pointing at R59.1. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading R59.1 alone.

I88Nonspecific lymphadenitis
I89Other noninfective disorders of lymphatic vessels and lymph nodes
L04Acute lymphadenitis
R22Localized swelling, mass and lump of skin and subcutaneous tissue

Risk adjustment

R59.1 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

R59.1 is named in 11 Medicare coverage policies — 11 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A55717Billing and Coding: Lab: Flow Cytometry
A56421Billing and Coding: CT of the Abdomen and Pelvis
A56448Billing and Coding: Breast Imaging Mammography/Breast Echography (Sonography)/Breast MRI/Ductography
A56464Billing and Coding: Flow Cytometry

How R59.1 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to R59.1.

Lymphadenopathy(generalized)
Lymphadenosis
Adenopathy›generalized
Enlargement, enlarged›lymph gland or node›generalized
Hypertrophy, hypertrophic›gland, glandular›generalized
Hypertrophy, hypertrophic›lymph, lymphatic gland›generalized
Swelling›glands›generalized

Code history

R59.1 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share R59. If R59.1 is not quite right, the correct code is usually one of these.

Questions about R59.1

Is R59.1 a billable ICD-10-CM code?: Yes. R59.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does R59.1 sit in the tabular list?: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99), in the block General symptoms and signs (R50-R69).
What cannot be coded together with R59.1?: R59.1 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above R59.1 (R59) and apply to it just the same.