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I21.B

I21.BMyocardial infarction with coronary microvascular dysfunction

Billable / specific codeICD-10-CM

I21.B is a billable, specific ICD-10-CM code for myocardial infarction with coronary microvascular dysfunction. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Myocardial infarction with coronary microvascular disease
  • Myocardial infarction with nonobstructive coronary arteries [MINOCA] with microvascular disease

Other codes that can never be billed with I21.B

These codes carry an Excludes1 note pointing at I21.B. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading I21.B alone.

  • I25.82Chronic total occlusion of coronary artery

Risk adjustment

I21.B risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 228 Acute Myocardial Infarction0.252 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

I21.B is named in 43 Medicare coverage policies 43 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52458Automatic External Defibrillators - Policy Article
  • A52458Automatic External Defibrillators - Policy Article
  • A53775Billing and Coding: Frequency and Duration for Cardiac Rehabilitation and Intensive Cardiac Rehabilitation
  • A56423Billing and Coding: Cardiology Non-emergent Outpatient Stress Testing

How I21.B is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to I21.B.

  • Dysfunctioncoronary microvascularwithmyocardial infarction
  • Infarct, infarctionmyocardium, myocardialwithcoronary microvascular disease
  • Infarct, infarctionmyocardium, myocardialwithcoronary microvascular dysfunction
  • Infarct, infarctionmyocardium, myocardialwithnonobstructive coronary arteries [MINOCA] with microvascular disease
  • Disease, diseasedcoronarymicrovascularwithmyocardial infarction

Related codes at this level

Codes that share I21. If I21.B is not quite right, the correct code is usually one of these.

Questions about I21.B

Is I21.B a billable ICD-10-CM code?
Yes. I21.B is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does I21.B sit in the tabular list?
Diseases of the circulatory system (I00-I99), in the block Ischemic heart diseases (I20-I25).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.