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E78.00

E78.00: Pure hypercholesterolemia, unspecified

Billable / specific codeICD-10-CM

E78.00 is a billable, specific ICD-10-CM code for pure hypercholesterolemia, unspecified. It is valid for submission on a claim.

Check E78.00 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Fredrickson's hyperlipoproteinemia, type IIa
  • Hyperbetalipoproteinemia
  • Low-density-lipoprotein-type [LDL] hyperlipoproteinemia
  • (Pure) hypercholesterolemia NOS

Excludes1 inherited from the categories above E78.00

A category’s note binds every code beneath it.

Written on E78: Disorders of lipoprotein metabolism and other lipidemias

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E78.00 is named in 22 Medicare coverage policies: 22 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A54543Therapeutic Apheresis for Familial Hypercholesterolemia
  • A56416Billing and Coding: Assays for Vitamins and Metabolic Function
  • A56422Billing and Coding: Bariatric Surgical Management of Morbid Obesity
  • A56774Billing and Coding: Ophthalmic Angiography (Fluorescein and Indocyanine Green)

Alphabetic index entries that lead here

  • Cholesteremia
  • Cholesterolemia(essential) (pure)
  • Hyperbetalipoproteinemia(familial)
  • Hypercholesterolemia(essential) (primary) (pure)
  • Low-density-lipoprotein-type hyperlipoproteinemia(LDL)
  • Cholesterol›elevated(high)
  • Elevated, elevation›cholesterol
  • Frederickson's hyperlipoproteinemia, type›IIA
  • High›cholesterol
  • Hyperlipoproteinemia›low-density-lipoprotein-type(LDL)
  • Xanthoma›hypercholesterinemic
  • Xanthoma›hypercholesterolemic

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E78.0

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.