Is E70.321 a billable ICD-10-CM code?

Yes. E70.321 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does E70.321 sit in the tabular list?

Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).

What cannot be coded together with E70.321?

E70.321 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E70.321 (E70.32) and apply to it just the same.

E70.321

E70.321 — Tyrosinase positive oculocutaneous albinism

Billable / specific codeICD-10-CM

E70.321 is a billable, specific ICD-10-CM code for tyrosinase positive oculocutaneous albinism. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Albinism II
Oculocutaneous albinism ty-pos

Excludes1 inherited from the categories above E70.321

These are not written on E70.321, but they bind it: a note on a category applies to every code beneath it. Billing E70.321 with anything listed here is a denial.

Written on E70.32 — Oculocutaneous albinism

Chediak-Higashi syndrome (E70.330)
Hermansky-Pudlak syndrome (E70.331)

Other codes that can never be billed with E70.321

These codes carry an Excludes1 note pointing at E70.321. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E70.321 alone.

E72Other disorders of amino-acid metabolism

Risk adjustment

E70.321 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

E70.321 is named in 3 Medicare coverage policies — 3 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A53060Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
A56726Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography)
A57071Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography)

How E70.321 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E70.321.

Albinism, albino›II
Albinism, albino›oculocutaneous›tyrosinase positive(ty)

Code history

E70.321 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share E70.32. If E70.321 is not quite right, the correct code is usually one of these.

Questions about E70.321

Is E70.321 a billable ICD-10-CM code?: Yes. E70.321 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E70.321 sit in the tabular list?: Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
What cannot be coded together with E70.321?: E70.321 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E70.321 (E70.32) and apply to it just the same.