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E70.21

E70.21: Tyrosinemia

Billable / specific codeICD-10-CM

E70.21 is a billable, specific ICD-10-CM code for tyrosinemia. It is valid for submission on a claim.

Check E70.21 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Hypertyrosinemia

Excludes1 inherited from the categories above E70.21

A category’s note binds every code beneath it.

Written on E70.2: Disorders of tyrosine metabolism

  • transitory tyrosinemia of newborn (P74.5)

Other codes that can never be billed with E70.21

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • E72Other disorders of amino-acid metabolism

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E70.21 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A53060Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
  • A56726Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography)
  • A57071Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography)

Alphabetic index entries that lead here

  • Hypertyrosinemia
  • Tyrosinemia
  • Tyrosinosis
  • Disorder›metabolism NOS›amino-acid›aromatic›tyrosine›hypertyrosinemia

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E70.2

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.