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E25.0

E25.0: Congenital adrenogenital disorders associated with enzyme deficiency

Billable / specific codeICD-10-CM

E25.0 is a billable, specific ICD-10-CM code for congenital adrenogenital disorders associated with enzyme deficiency. It is valid for submission on a claim.

Check E25.0 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Congenital adrenal hyperplasia
  • 21-Hydroxylase deficiency
  • Salt-losing congenital adrenal hyperplasia

Excludes1 inherited from the categories above E25.0

A category’s note binds every code beneath it.

Written on E25: Adrenogenital disorders

  • indeterminate sex and pseudohermaphroditism (Q56)
  • chromosomal abnormalities (Q90-Q99)

Other codes that can never be billed with E25.0

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • E24Cushing's syndrome
  • E30.1Precocious puberty
  • Q56Indeterminate sex and pseudohermaphroditism
  • Q89.1Congenital malformations of adrenal gland

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E25.0 is named in 6 Medicare coverage policies: 6 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55336Billing and Coding: Retroperitoneal Ultrasound
  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A56619Billing and Coding: Nerve Conduction Studies and Electromyography
  • A57204Billing and Coding: MRI and CT Scans of the Head and Neck

Alphabetic index entries that lead here

  • Adrenogenitalism, congenital
  • Adrenogenital syndrome›congenital
  • Adrenogenital syndrome›salt loss
  • Defect, defective›11-hydroxylase
  • Defect, defective›21-hydroxylase
  • Defect, defective›3-beta-hydroxysteroid dehydrogenase
  • Deficiency, deficient›11-hydroxylase
  • Deficiency, deficient›21-hydroxylase
  • Deficiency, deficient›3-beta hydroxysteroid dehydrogenase
  • Hyperadrenocorticism›congenital
  • Macrogenitosomia›congenital
  • Masculinization with adrenal hyperplasia›congenital

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E25

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.