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E25.0

E25.0Congenital adrenogenital disorders associated with enzyme deficiency

Billable / specific codeICD-10-CM

E25.0 is a billable, specific ICD-10-CM code for congenital adrenogenital disorders associated with enzyme deficiency. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Congenital adrenal hyperplasia
  • 21-Hydroxylase deficiency
  • Salt-losing congenital adrenal hyperplasia

Other codes that can never be billed with E25.0

These codes carry an Excludes1 note pointing at E25.0. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E25.0 alone.

  • Q89.1Congenital malformations of adrenal gland
  • E24Cushing's syndrome
  • E30.1Precocious puberty

Risk adjustment

E25.0 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

E25.0 is named in 6 Medicare coverage policies 6 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A55336Billing and Coding: Retroperitoneal Ultrasound
  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A56619Billing and Coding: Nerve Conduction Studies and Electromyography
  • A57204Billing and Coding: MRI and CT Scans of the Head and Neck

How E25.0 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E25.0.

  • Adrenogenitalism, congenital
  • Adrenogenital syndromecongenital
  • Adrenogenital syndromesalt loss
  • Defect, defective11-hydroxylase
  • Defect, defective21-hydroxylase
  • Defect, defective3-beta-hydroxysteroid dehydrogenase
  • Deficiency, deficient11-hydroxylase
  • Deficiency, deficient21-hydroxylase
  • Deficiency, deficient3-beta hydroxysteroid dehydrogenase
  • Hyperadrenocorticismcongenital
  • Macrogenitosomiacongenital
  • Masculinization with adrenal hyperplasiacongenital

Related codes at this level

Codes that share E25. If E25.0 is not quite right, the correct code is usually one of these.

Questions about E25.0

Is E25.0 a billable ICD-10-CM code?
Yes. E25.0 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E25.0 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Disorders of other endocrine glands (E20-E35).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.