E10.321 — Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema
E10.321 is a non-billable header ICD-10-CM code for type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.
This code requires a 7th character
One of the following 7th characters is to be assigned to codes in subcategory E10.32 to designate laterality of the disease:
- 1
- right eye
- 2
- left eye
- 3
- bilateral
- 9
- unspecified eye
Excludes1 inherited from the categories above E10.321
These are not written on E10.321, but they bind it: a note on a category applies to every code beneath it. Billing E10.321 with anything listed here is a denial.
Written on E10 — Type 1 diabetes mellitus
- diabetes mellitus due to underlying condition (E08.-)
- drug or chemical induced diabetes mellitus (E09.-)
- gestational diabetes (O24.4-)
- hyperglycemia NOS (R73.9)
- neonatal diabetes mellitus (P70.2)
- postpancreatectomy diabetes mellitus (E13.-)
- postprocedural diabetes mellitus (E13.-)
- secondary diabetes mellitus NEC (E13.-)
- type 2 diabetes mellitus (E11.-)
Other codes that can never be billed with E10.321
These codes carry an Excludes1 note pointing at E10.321. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E10.321 alone.
Risk adjustment
E10.321 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
How E10.321 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E10.321.
- Diabetes, diabetic›type 1›with›retinopathy›nonproliferative›with macular edema
- Diabetes, diabetic›type 1›with›retinopathy›nonproliferative›mild›with macular edema
Code history
E10.321 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.
Code to one of these instead E10.321
4 child codes. Green means billable.
- E10.3211Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema, right eye
- E10.3212Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema, left eye
- E10.3213Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema, bilateral
- E10.3219Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema, unspecified eye
Related codes at this level
Codes that share E10.32. If E10.321 is not quite right, the correct code is usually one of these.
Questions about E10.321
- Is E10.321 a billable ICD-10-CM code?
- No. E10.321 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
- Where does E10.321 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Diabetes mellitus (E08-E13).
- What cannot be coded together with E10.321?
- E10.321 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E10.321 (E10) and apply to it just the same.