MCMedicalCodingSoftware
D84.821

D84.821: Immunodeficiency due to drugs

Billable / specific codeICD-10-CM

D84.821 is a billable, specific ICD-10-CM code for immunodeficiency due to drugs. It is valid for submission on a claim.

Check D84.821 with the rest of the claim: free scrubber

Use additional code

Add a secondary code to capture the detail described below.

  • code for adverse effect if applicable, to identify adverse effect of drug (T36-T50 with fifth or six character 5)
  • code, if applicable, for associated long term (current) drug therapy drug or medication such as:
  • long term (current) drug therapy systemic steroids (Z79.52)
  • other long term (current) drug therapy (Z79.899)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Immunodeficiency due to (current or past) medication

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D84.821 is named in 10 Medicare coverage policies: 10 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56464Billing and Coding: Flow Cytometry
  • A56638Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
  • A56642Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
  • A57044Billing and Coding: Removal of Benign Skin Lesions

Alphabetic index entries that lead here

  • Immunodeficiency›due to›drugs
  • Immunodeficiency›due to›medication(current or past)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D84.82

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.