MCMedicalCodingSoftware
D72.81

D72.81Decreased white blood cell count

Non-billable headerICD-10-CM

D72.81 is a non-billable header ICD-10-CM code for decreased white blood cell count. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes2 — not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • neutropenia (D70)

Excludes1 inherited from the categories above D72.81

These are not written on D72.81, but they bind it: a note on a category applies to every code beneath it. Billing D72.81 with anything listed here is a denial.

Written on D72.8 Other specified disorders of white blood cells

Written on D72 Other disorders of white blood cells

Excludes2 inherited from the categories above D72.81

Also inherited, and the opposite of Excludes1: these conditions are not part of D72.81, but a patient can have both, so you may code both.

Written on D72 Other disorders of white blood cells

  • neutropenia (D70)

Risk adjustment

D72.81 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code history

D72.81 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Code to one of these instead D72.81

3 child codes. Green means billable.

Related codes at this level

Codes that share D72.8. If D72.81 is not quite right, the correct code is usually one of these.

Questions about D72.81

Is D72.81 a billable ICD-10-CM code?
No. D72.81 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does D72.81 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Other disorders of blood and blood-forming organs (D70-D77).
What cannot be coded together with D72.81?
D72.81 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D72.81 (D72.8, D72) and apply to it just the same.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.