MCMedicalCodingSoftware
D72.0

D72.0: Genetic anomalies of leukocytes

Billable / specific codeICD-10-CM

D72.0 is a billable, specific ICD-10-CM code for genetic anomalies of leukocytes. It is valid for submission on a claim.

Check D72.0 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • Chédiak (-Steinbrinck)-Higashi syndrome (E70.330)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Alder (granulation) (granulocyte) anomaly
  • Alder syndrome
  • Hereditary leukocytic hypersegmentation
  • Hereditary leukocytic hyposegmentation
  • Hereditary leukomelanopathy
  • May-Hegglin (granulation) (granulocyte) anomaly
  • May-Hegglin syndrome
  • Pelger-Huët (granulation) (granulocyte) anomaly
  • Pelger-Huët syndrome

Excludes1 inherited from the categories above D72.0

A category’s note binds every code beneath it.

Written on D72: Other disorders of white blood cells

Excludes2 inherited from the categories above D72.0

Not part of this code, but both may be coded when both are present.

Written on D72: Other disorders of white blood cells

  • neutropenia (D70)

Risk adjustment

D72.0 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D72.0 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A57689Billing and Coding: Lab: Flow Cytometry

Alphabetic index entries that lead here

  • Alder(-Reilly) anomaly or syndrome (leukocyte granulation)
  • Dohle body panmyelopathic syndrome
  • Hegglin's anomaly or syndrome
  • Hypersegmentation, leukocytic, hereditary
  • Hyposegmentation, leukocytic, hereditary
  • Jordan's anomaly or syndrome
  • Leukomelanopathy, hereditary
  • May anomaly or syndrome(-Hegglin)
  • Neutrophilia, hereditary giant
  • Pelger-Huët anomaly or syndrome
  • Anomaly, anomalous›Alder(-Reilly) (leukocyte granulation)
  • Anomaly, anomalous›granulation or granulocyte, genetic(constitutional) (leukocyte)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D72

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.