D72.0 — Genetic anomalies of leukocytes
D72.0 is a billable, specific ICD-10-CM code for genetic anomalies of leukocytes. It is valid for submission on a claim.
Excludes1 — never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
- Chédiak (-Steinbrinck)-Higashi syndrome (E70.330)
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Alder (granulation) (granulocyte) anomaly
- Alder syndrome
- Hereditary leukocytic hypersegmentation
- Hereditary leukocytic hyposegmentation
- Hereditary leukomelanopathy
- May-Hegglin (granulation) (granulocyte) anomaly
- May-Hegglin syndrome
- Pelger-Huët (granulation) (granulocyte) anomaly
- Pelger-Huët syndrome
Excludes1 inherited from the categories above D72.0
These are not written on D72.0, but they bind it: a note on a category applies to every code beneath it. Billing D72.0 with anything listed here is a denial.
Excludes2 inherited from the categories above D72.0
Also inherited, and the opposite of Excludes1: these conditions are not part of D72.0, but a patient can have both, so you may code both.
Risk adjustment
D72.0 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
D72.0 is named in 3 Medicare coverage policies — 3 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A55717Billing and Coding: Lab: Flow Cytometry
- A56464Billing and Coding: Flow Cytometry
- A57689Billing and Coding: Lab: Flow Cytometry
How D72.0 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D72.0.
- Alder(-Reilly) anomaly or syndrome (leukocyte granulation)
- Dohle body panmyelopathic syndrome
- Hegglin's anomaly or syndrome
- Hypersegmentation, leukocytic, hereditary
- Hyposegmentation, leukocytic, hereditary
- Jordan's anomaly or syndrome
- Leukomelanopathy, hereditary
- May anomaly or syndrome(-Hegglin)
- Neutrophilia, hereditary giant
- Pelger-Huët anomaly or syndrome
- Anomaly, anomalous›Alder(-Reilly) (leukocyte granulation)
- Anomaly, anomalous›granulation or granulocyte, genetic(constitutional) (leukocyte)
Code history
D72.0 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.
Related codes at this level
Codes that share D72. If D72.0 is not quite right, the correct code is usually one of these.
Questions about D72.0
- Is D72.0 a billable ICD-10-CM code?
- Yes. D72.0 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does D72.0 sit in the tabular list?
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Other disorders of blood and blood-forming organs (D70-D77).
- What cannot be coded together with D72.0?
- D72.0 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D72.0 (D72) and apply to it just the same.