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D68.021

D68.021Von Willebrand disease, type 2B

Billable / specific codeICD-10-CM

D68.021 is a billable, specific ICD-10-CM code for von willebrand disease, type 2b. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss
  • Qualitative defects of von Willebrand factor with hyper-adhesive forms
  • Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb

Risk adjustment

D68.021 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 112 Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions0.450 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

D68.021 is named in 4 Medicare coverage policies 4 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56065Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3
  • A57954Billing and Coding: Routine Foot Care
  • A59105Billing and Coding: Off-Label Use of Intravenous Immune Globulin (IVIG)
  • A60187Billing and Coding: Off-Label Use of Intravenous Immune Globulin (IVIG)

How D68.021 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D68.021.

  • Defect, defectivequalitative, of von Willebrand factorwithhigh-molecular-weight von Willebrand factor loss
  • Defect, defectivequalitative, of von Willebrand factorwithhyper-adhesive forms
  • Defect, defectivequalitative, of von Willebrand factorwithincreased affinity for platelet glycoprotein lb
  • Disease, diseasedvon Willebrandtype 2type 2B

Related codes at this level

Codes that share D68.02. If D68.021 is not quite right, the correct code is usually one of these.

Questions about D68.021

Is D68.021 a billable ICD-10-CM code?
Yes. D68.021 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D68.021 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Coagulation defects, purpura and other hemorrhagic conditions (D65-D69).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.