MCMedicalCodingSoftware
D64.81

D64.81: Anemia due to antineoplastic chemotherapy

Billable / specific codeICD-10-CM

D64.81 is a billable, specific ICD-10-CM code for anemia due to antineoplastic chemotherapy. It is valid for submission on a claim.

Check D64.81 with the rest of the claim: free scrubber

Excludes2: not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • anemia in neoplastic disease (D63.0)
  • aplastic anemia due to antineoplastic chemotherapy (D61.1)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Antineoplastic chemotherapy induced anemia

Excludes1 inherited from the categories above D64.81

A category’s note binds every code beneath it.

Written on D64: Other anemias

  • refractory anemia (D46.-)
  • refractory anemia with excess blasts in transformation [RAEB T] (C92.0-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D64.81 is named in 7 Medicare coverage policies: 7 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56464Billing and Coding: Flow Cytometry
  • A56795Billing and Coding: Erythropoiesis Stimulating Agents (ESAs)
  • A58710Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
  • A58720Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing

Alphabetic index entries that lead here

  • Anemia›due to›antineoplastic chemotherapy
  • Anemia›due to›chemotherapy, antineoplastic

The condition this code belongs to

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D64.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.