D61.81 — Pancytopenia
D61.81 is a non-billable header ICD-10-CM code for pancytopenia. It cannot be billed on its own: choose one of the more specific child codes below.
Excludes1 — never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
- pancytopenia (due to) (with) aplastic anemia (D61.9)
- pancytopenia (due to) (with) bone marrow infiltration (D61.82)
- pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)
- pancytopenia (due to) (with) hairy cell leukemia (C91.4-)
- pancytopenia (due to) (with) human immunodeficiency virus disease (B20.-)
- pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)
- pancytopenia (due to) (with) myeloproliferative disease (D47.1)
Excludes2 — not included here, but may coexist
The excluded condition is not part of this code, but a patient can have both. You may code both.
- pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)
Risk adjustment
D61.81 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
Code history
D61.81 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.
Code to one of these instead D61.81
3 child codes. Green means billable.
Related codes at this level
Codes that share D61.8. If D61.81 is not quite right, the correct code is usually one of these.
Questions about D61.81
- Is D61.81 a billable ICD-10-CM code?
- No. D61.81 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
- Where does D61.81 sit in the tabular list?
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Aplastic and other anemias and other bone marrow failure syndromes (D60-D64).
- What cannot be coded together with D61.81?
- D61.81 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter.