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D61.81

D61.81: Pancytopenia

Non-billable headerICD-10-CM

D61.81 is a non-billable header ICD-10-CM code for pancytopenia. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • pancytopenia (due to) (with) aplastic anemia (D61.9)
  • pancytopenia (due to) (with) bone marrow infiltration (D61.82)
  • pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)
  • pancytopenia (due to) (with) hairy cell leukemia (C91.4-)
  • pancytopenia (due to) (with) human immunodeficiency virus disease (B20.-)
  • pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)
  • pancytopenia (due to) (with) myeloproliferative disease (D47.1)

Excludes2: not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)

Excludes2 inherited from the categories above D61.81

Not part of this code, but both may be coded when both are present.

Written on D61: Other aplastic anemias and other bone marrow failure syndromes

  • neutropenia (D70.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead D61.81

3 child codes. Green means billable.

Other codes under D61.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.