Is D52.1 a billable ICD-10-CM code?

Yes. D52.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does D52.1 sit in the tabular list?

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Nutritional anemias (D50-D53).

What cannot be coded together with D52.1?

D52.1 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D52.1 (D52) and apply to it just the same.

D52.1

D52.1 — Drug-induced folate deficiency anemia

Billable / specific codeICD-10-CM

D52.1 is a billable, specific ICD-10-CM code for drug-induced folate deficiency anemia. It is valid for submission on a claim.

Use additional code

Add a secondary code to capture the detail described below.

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Excludes1 inherited from the categories above D52.1

These are not written on D52.1, but they bind it: a note on a category applies to every code beneath it. Billing D52.1 with anything listed here is a denial.

Written on D52 — Folate deficiency anemia

folate deficiency without anemia (E53.8)

Other codes that can never be billed with D52.1

These codes carry an Excludes1 note pointing at D52.1. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D52.1 alone.

E53.8Deficiency of other specified B group vitamins

Risk adjustment

D52.1 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D52.1 is named in 4 Medicare coverage policies — 4 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A56416Billing and Coding: Assays for Vitamins and Metabolic Function
A56464Billing and Coding: Flow Cytometry
A56675Billing and Coding: Homocysteine Level, Serum
A57755Billing and Coding: Vitamin B<sub>12</sub> Injections

How D52.1 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D52.1.

Anemia›deficiency›folate›drug-induced
Anemia›deficiency›folic acid›drug-induced
Anemia›due to›deficiency›folate›drug-induced

Code history

D52.1 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share D52. If D52.1 is not quite right, the correct code is usually one of these.

Questions about D52.1

Is D52.1 a billable ICD-10-CM code?: Yes. D52.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D52.1 sit in the tabular list?: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Nutritional anemias (D50-D53).
What cannot be coded together with D52.1?: D52.1 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above D52.1 (D52) and apply to it just the same.