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D49.89

D49.89: Neoplasm of unspecified behavior of other specified sites

Billable / specific codeICD-10-CM

D49.89 is a billable, specific ICD-10-CM code for neoplasm of unspecified behavior of other specified sites. It is valid for submission on a claim.

Check D49.89 with the rest of the claim: free scrubber

Excludes1 inherited from the categories above D49.89

A category’s note binds every code beneath it.

Written on D49.8: Neoplasm of unspecified behavior of other specified sites

  • neoplasm of unspecified behavior of eyelid (skin) (D49.2)
  • neoplasm of unspecified behavior of eyelid cartilage (D49.2)
  • neoplasm of unspecified behavior of great vessels (D49.2)
  • neoplasm of unspecified behavior of optic nerve (D49.7)

Excludes2 inherited from the categories above D49.89

Not part of this code, but both may be coded when both are present.

Written on D49: Neoplasms of unspecified behavior

  • neoplasms of uncertain behavior (D37-D44, D48)

Other codes that can never be billed with D49.89

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • D49.2Neoplasm of unspecified behavior of bone, soft tissue, and skin

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D49.89 is named in 27 Medicare coverage policies: 27 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52868Billing and Coding: Transesophageal Echocardiography (TEE)
  • A52986Billing and Coding: Biomarkers for Oncology
  • A53060Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography

Alphabetic index entries that lead here

  • Osteitis›deformans›in›neoplastic disease›multiple sites

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D49.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.