C21.2 — Malignant neoplasm of cloacogenic zone
C21.2 is a billable, specific ICD-10-CM code for malignant neoplasm of cloacogenic zone. It is valid for submission on a claim.
Risk adjustment
C21.2 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 22 Bladder, Colorectal, and Other Cancers0.363 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
C21.2 is named in 96 Medicare coverage policies — 96 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A52370Billing and Coding: Bevacizumab and biosimilars
- A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
- A52479Oral Anticancer Drugs - Policy Article
- A52479Oral Anticancer Drugs - Policy Article
How C21.2 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to C21.2.
- Carcinoma›cloacogenic›unspecified site
Related codes at this level
Codes that share C21. If C21.2 is not quite right, the correct code is usually one of these.
Questions about C21.2
- Is C21.2 a billable ICD-10-CM code?
- Yes. C21.2 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does C21.2 sit in the tabular list?
- Neoplasms (C00-D49), in the block Malignant neoplasms of digestive organs (C15-C26).