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A53.0

A53.0Latent syphilis, unspecified as early or late

Billable / specific codeICD-10-CM

A53.0 is a billable, specific ICD-10-CM code for latent syphilis, unspecified as early or late. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Latent syphilis NOS
  • Positive serological reaction for syphilis

Risk adjustment

A53.0 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How A53.0 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to A53.0.

  • Positiveserology for syphilis
  • PositiveVDRL
  • PositiveWassermann reaction
  • Serology for syphilispositive
  • Serology for syphilisreactivated
  • Syphilis, syphiliticlatent
  • Syphilis, syphiliticlatentdate of infection unspecified
  • Syphilis, syphiliticlatentfollow-up of latent syphilis
  • Syphilis, syphiliticlatentpositive serology(only finding)
  • Syphilis, syphiliticlatentfollow-up of latent syphilisdate of infection unspecified
  • Syphilis, syphiliticlatentpositive serologydate of infection unspecified

Related codes at this level

Codes that share A53. If A53.0 is not quite right, the correct code is usually one of these.

Questions about A53.0

Is A53.0 a billable ICD-10-CM code?
Yes. A53.0 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does A53.0 sit in the tabular list?
Certain infectious and parasitic diseases (A00-B99), in the block Infections with a predominantly sexual mode of transmission (A50-A64).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.