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ICD-10-CM tabular list

A50-A64Infections with a predominantly sexual mode of transmission

ICD-10-CM codes A50-A64 cover infections with a predominantly sexual mode of transmission, within certain infectious and parasitic diseases. The block holds 169 codes across 13 categories, of which 142 are billable and 27 are header codes that cannot be submitted on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • nonspecific and nongonococcal urethritis (N34.1)
  • Reiter's disease (M02.3-)

Excludes2 — not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • human immunodeficiency virus [HIV] disease (B20)

Risk adjustment in A50-A64

0 codes in this block map to a CMS-HCC, which means the diagnosis carries a risk-adjustment payment when it is documented and coded. Under-coding here is money left on the table; over-coding here is what audits are for.

  • HCC 92 Bone/Joint/Muscle/Severe Soft Tissue Infections/Necrosis
  • HCC 2 Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock
  • HCC 78 Intestinal Obstruction/Perforation

What else to watch in A50-A64

  • 80 codes are named in Medicare coverage policies. An LCD or NCD lists them as supporting medical necessity, or explicitly as not supporting it. Which applies depends on the MAC for your state.

Categories in A50-A64

ICD-10-CMFY2026-Apr· effective April 1, 2026