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A41.50

A41.50Gram-negative sepsis, unspecified

Billable / specific codeICD-10-CM

A41.50 is a billable, specific ICD-10-CM code for gram-negative sepsis, unspecified. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Gram-negative sepsis NOS

Risk adjustment

A41.50 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 2 Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock0.500 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

A41.50 is named in 18 Medicare coverage policies 18 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52868Billing and Coding: Transesophageal Echocardiography (TEE)
  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A56625Billing and Coding: Echocardiography
  • A56781Billing and Coding: Transthoracic Echocardiography (TTE)

How A41.50 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to A41.50.

  • SepsisGram-negative(organism)

Related codes at this level

Codes that share A41.5. If A41.50 is not quite right, the correct code is usually one of these.

Questions about A41.50

Is A41.50 a billable ICD-10-CM code?
Yes. A41.50 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does A41.50 sit in the tabular list?
Certain infectious and parasitic diseases (A00-B99), in the block Other bacterial diseases (A30-A49).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.