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A41.4

A41.4Sepsis due to anaerobes

Billable / specific codeICD-10-CM

A41.4 is a billable, specific ICD-10-CM code for sepsis due to anaerobes. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

Risk adjustment

A41.4 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 2 Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock0.500 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

A41.4 is named in 17 Medicare coverage policies 17 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52868Billing and Coding: Transesophageal Echocardiography (TEE)
  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A56505Billing and Coding: Transesophageal Echocardiography (TEE)
  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax

How A41.4 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to A41.4.

  • Sepsisanaerobic
  • SepsisGram-negativeanaerobic
  • Infection, infected, infectiveClostridioidesdifficilesepsis
  • Infection, infected, infectiveClostridium NECdifficilesepsis
  • Infection, infected, infectiveClostridium NECperfringenssepsis
  • Infection, infected, infectiveClostridium NECwelchiisepsis

Related codes at this level

Codes that share A41. If A41.4 is not quite right, the correct code is usually one of these.

Questions about A41.4

Is A41.4 a billable ICD-10-CM code?
Yes. A41.4 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does A41.4 sit in the tabular list?
Certain infectious and parasitic diseases (A00-B99), in the block Other bacterial diseases (A30-A49).
What cannot be coded together with A41.4?
A41.4 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.