MCMedicalCodingSoftware
S5553

S5553: Insulin, long acting; 5 units

HCPCSActiveBETOS Z2

S5553 is a HCPCS Level II code for insulin, long acting; 5 units. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it: see the coverage note below before you bill it.

Medicare coverage: Not payable by Medicare

Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.

From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.

Physician fee schedule statusI

Not valid for Medicare purposes. Medicare uses another code.

Global period: XXX

Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.

The CMS record for S5553

Long descriptor
Insulin, long acting; 5 units

The official wording. This is what the code means.

Short descriptor
Insulin long acting 5 u

CMS's 28-character form, which is what shows up on a remittance advice.

Added
October 1, 2003

When CMS introduced the code.

BETOS
Z2

Berenson-Eggers Type of Service: CMS's own analytic grouping.

Pricing indicator
00: Not priced by Part B

Service not separately priced by Part B, not covered, bundled into another service, or used by Part A only.

Codes adjacent to S5553

HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If S5553 is not quite right, the correct code is very often within a few positions of it.

  • S5518Home infusion therapy, all supplies necessary for catheter repair
  • S5520Home infusion therapy, all supplies (including catheter) necessary for a peripherally inserted central venous catheter (picc) line insertion
  • S5521Home infusion therapy, all supplies (including catheter) necessary for a midline catheter insertion
  • S5522Home infusion therapy, insertion of peripherally inserted central venous catheter (picc), nursing services only (no supplies or catheter included)
  • S5523Home infusion therapy, insertion of midline venous catheter, nursing services only (no supplies or catheter included)
  • S5550Insulin, rapid onset, 5 units
  • S5551Insulin, most rapid onset (lispro or aspart); 5 units
  • S5552Insulin, intermediate acting (nph or lente); 5 units
  • S5560Insulin delivery device, reusable pen; 1.5 ml size
  • S5561Insulin delivery device, reusable pen; 3 ml size
  • S5565Insulin cartridge for use in insulin delivery device other than pump; 150 units
  • S5566Insulin cartridge for use in insulin delivery device other than pump; 300 units
  • S5570Insulin delivery device, disposable pen (including insulin); 1.5 ml size
  • S5571Insulin delivery device, disposable pen (including insulin); 3 ml size
  • S8030Scleral application of tantalum ring(s) for localization of lesions for proton beam therapy
  • S8032Low-dose computed tomography for lung cancer screeningterminated
HCPCS Level II2026Q4-Oct· effective October 1, 2026