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S3645

S3645: Hiv-1 antibody testing of oral mucosal transudate

HCPCSActiveBETOS Z2

S3645 is a HCPCS Level II code for hiv-1 antibody testing of oral mucosal transudate. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it: see the coverage note below before you bill it.

Medicare coverage: Not payable by Medicare

Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.

From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.

Physician fee schedule statusI

Not valid for Medicare purposes. Medicare uses another code.

Global period: XXX

Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.

The CMS record for S3645

Long descriptor
Hiv-1 antibody testing of oral mucosal transudate

The official wording. This is what the code means.

Short descriptor
Hiv-1 antibody testing of or

CMS's 28-character form, which is what shows up on a remittance advice.

Added
January 1, 2000

When CMS introduced the code.

BETOS
Z2

Berenson-Eggers Type of Service: CMS's own analytic grouping.

Pricing indicator
00: Not priced by Part B

Service not separately priced by Part B, not covered, bundled into another service, or used by Part A only.

Codes adjacent to S3645

HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If S3645 is not quite right, the correct code is very often within a few positions of it.

  • S2411Fetoscopic laser therapy for treatment of twin-to-twin transfusion syndrome
  • S2900Surgical techniques requiring use of robotic surgical system (list separately in addition to code for primary procedure)
  • S3000Diabetic indicator; retinal eye exam, dilated, bilateral
  • S3005Performance measurement, evaluation of patient self assessment, depression
  • S3600Stat laboratory request (situations other than s3601)
  • S3601Emergency stat laboratory charge for patient who is homebound or residing in a nursing facility
  • S3620Newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total)
  • S3630Eosinophil count, blood, direct
  • S3650Saliva test, hormone level; during menopause
  • S3652Saliva test, hormone level; to assess preterm labor risk
  • S3655Antisperm antibodies test (immunobead)
  • S3708Gastrointestinal fat absorption study
  • S3721Prostate cancer antigen 3 (pca3) testingterminated
  • S3722Dose optimization by area under the curve (auc) analysis, for infusional 5-fluorouracil
  • S3800Genetic testing for amyotrophic lateral sclerosis (als)
  • S3840Dna analysis for germline mutations of the ret proto-oncogene for susceptibility to multiple endocrine neoplasia type 2
HCPCS Level II2026Q4-Oct· effective October 1, 2026