S2120: Low density lipoprotein (ldl) apheresis using heparin-induced extracorporeal ldl precipitation
S2120 is a HCPCS Level II code for low density lipoprotein (ldl) apheresis using heparin-induced extracorporeal ldl precipitation. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it: see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S2120
- Long descriptor
- Low density lipoprotein (ldl) apheresis using heparin-induced extracorporeal ldl precipitation
- Short descriptor
- Low density lipoprotein(ldl)
- Added
- January 1, 2001
- BETOS
- Z2
- Pricing indicator
- 00: Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service: CMS's own analytic grouping.
Service not separately priced by Part B, not covered, bundled into another service, or used by Part A only.
Codes adjacent to S2120
HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If S2120 is not quite right, the correct code is very often within a few positions of it.
- S2095Transcatheter occlusion or embolization for tumor destruction, percutaneous, any method, using yttrium-90 microspheres
- S2102Islet cell tissue transplant from pancreas; allogeneic
- S2103Adrenal tissue transplant to brain
- S2107Adoptive immunotherapy i.e. development of specific anti-tumor reactivity (e.g., tumor-infiltrating lymphocyte therapy) per course of treatment
- S2112Arthroscopy, knee, surgical for harvesting of cartilage (chondrocyte cells)
- S2115Osteotomy, periacetabular, with internal fixation
- S2117Arthroereisis, subtalar
- S2118Metal-on-metal total hip resurfacing, including acetabular and femoral components
- S2140Cord blood harvesting for transplantation, allogeneic
- S2142Cord blood-derived stem-cell transplantation, allogeneic
- S2150Bone marrow or blood-derived stem cells (peripheral or umbilical), allogeneic or autologous, harvesting, transplantation, and related complications; including: pheresis and cell preparation/storage; marrow ablative therapy; drugs, supplies, hospitalization with outpatient follow-up; medical/surgical, diagnostic, emergency, and rehabilitative services; and the number of days of pre-and post-transplant care in the global definition
- S2152Solid organ(s), complete or segmental, single organ or combination of organs; deceased or living donor(s), procurement, transplantation, and related complications; including: drugs; supplies; hospitalization with outpatient follow-up; medical/surgical, diagnostic, emergency, and rehabilitative services, and the number of days of pre- and post-transplant care in the global definition
- S2202Echosclerotherapy
- S2205Minimally invasive direct coronary artery bypass surgery involving mini-thoracotomy or mini-sternotomy surgery, performed under direct vision; using arterial graft(s), single coronary arterial graft
- S2206Minimally invasive direct coronary artery bypass surgery involving mini-thoracotomy or mini-sternotomy surgery, performed under direct vision; using arterial graft(s), two coronary arterial grafts
- S2207Minimally invasive direct coronary artery bypass surgery involving mini-thoracotomy or mini-sternotomy surgery, performed under direct vision; using venous graft only, single coronary venous graft