J7525 — Tacrolimus, parenteral, 5 mg
J7525 is a HCPCS Level II code for tacrolimus, parenteral, 5 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
Medically Unlikely Edits — units per day
The most units of J7525 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.
- practitioner
- 2 units MAI 3 — Date of Service Edit: Clinical · Prescribing Information
- outpatient
- 2 units MAI 3 — Date of Service Edit: Clinical · Prescribing Information
- DME supplier
- 0 — never payable MAI 3 — Date of Service Edit: Clinical · Published Contractor Policy
The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.
The CMS record for J7525
- Long descriptor
- Tacrolimus, parenteral, 5 mg
- Short descriptor
- Tacrolimus injection
- Added
- January 1, 2001
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J7525
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J7525 is not quite right, the correct code is very often within a few positions of it.
- J7514Mycophenolate mofetil (myhibbin), oral suspension, 100 mg
- J7515Cyclosporine, oral, 25 mg
- J7516Injection, cyclosporine, 250 mg
- J7517Mycophenolate mofetil, oral, 250 mg
- J7518Mycophenolic acid, oral, 180 mg
- J7519Injection, mycophenolate mofetil, 10 mg
- J7520Sirolimus, oral, 1 mg
- J7521Tacrolimus, granules, oral suspension, 0.1 mg
- J7527Everolimus, oral, 0.25 mg
- J7528Mycophenolate mofetil, for suspension, oral, 100 mg
- J7599Immunosuppressive drug, not otherwise classified
- J7601Ensifentrine, inhalation suspension, fda approved final product, non-compounded, administered through dme, unit dose form, 3 mg
- J7604Acetylcysteine, inhalation solution, compounded product, administered through dme, unit dose form, per gram
- J7605Arformoterol, inhalation solution, fda approved final product, non-compounded, administered through dme, unit dose form, 15 micrograms
- J7606Formoterol fumarate, inhalation solution, fda approved final product, non-compounded, administered through dme, unit dose form, 20 micrograms
- J7607Levalbuterol, inhalation solution, compounded product, administered through dme, concentrated form, 0.5 mg
Questions about J7525
What is HCPCS code J7525?
J7525 is a HCPCS Level II code for tacrolimus, parenteral, 5 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J7525?
The CMS HCPCS file marks J7525 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
How is J7525 paid under the physician fee schedule?
J7525 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).