MCMedicalCodingSoftware
J7521

J7521: Tacrolimus, granules, oral suspension, 0.1 mg

HCPCSActiveBETOS O1E

J7521 is a HCPCS Level II code for tacrolimus, granules, oral suspension, 0.1 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.

Medicare coverage: Special coverage instructions apply

There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.

From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.

Physician fee schedule statusE

Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).

Global period: XXX

Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.

Medically Unlikely Edits: units per day

The most units of J7521 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.

practitioner
300 units
MAI 3: Date of Service Edit: Clinical · Prescribing Information
outpatient
300 units
MAI 3: Date of Service Edit: Clinical · Prescribing Information
DME supplier
2160 units
MAI 3: Date of Service Edit: Clinical · Clinical: Data

The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute, no documentation overrides it. CMS MUE 2026Q4.

The CMS record for J7521

Long descriptor
Tacrolimus, granules, oral suspension, 0.1 mg

The official wording. This is what the code means.

Short descriptor
Tacrolim granules oral susp

CMS's 28-character form, which is what shows up on a remittance advice.

Added
April 1, 2025

When CMS introduced the code.

BETOS
O1E

Berenson-Eggers Type of Service: CMS's own analytic grouping.

Pricing indicator
51: Other

Drugs.

Codes adjacent to J7521

HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If J7521 is not quite right, the correct code is very often within a few positions of it.

  • J7513Daclizumab, parenteral, 25 mgterminated
  • J7514Mycophenolate mofetil (myhibbin), oral suspension, 100 mgterminated
  • J7515Cyclosporine, oral, 25 mg
  • J7516Injection, cyclosporine, 250 mg
  • J7517Mycophenolate mofetil, oral, 250 mgterminated
  • J7518Mycophenolic acid, oral, 180 mg
  • J7519Injection, mycophenolate mofetil, 10 mgterminated
  • J7520Sirolimus, oral, 1 mg
  • J7524Mycophenolate mofetil, oral, 5 mg
  • J7525Tacrolimus, parenteral, 5 mg
  • J7526Injection, mycophenolate mofetil, 5 mg
  • J7527Everolimus, oral, 0.25 mg
  • J7528Mycophenolate mofetil, for suspension, oral, 100 mgterminated
  • J7529Mycophenolate mofetil, for suspension, oral, 5 mg
  • J7530Mycophenolate mofetil (myhibbin), oral suspension, 5 mg
  • J7531Prednisolone sodium phosphate, orally disintegrating tablet, 1 mg
HCPCS Level II2026Q4-Oct· effective October 1, 2026