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Z29.81

Z29.81Encounter for HIV pre-exposure prophylaxis

Billable / specific codeICD-10-CMPOA exempt

Z29.81 is a billable, specific ICD-10-CM code for encounter for hiv pre-exposure prophylaxis. It is valid for submission on a claim.

Code also

Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.

  • , if applicable, risk factors for HIV, such as:
  • contact with and (suspected) exposure to human immunodeficiency virus [HIV] (Z20.6)
  • high risk sexual behavior (Z72.5-)

Risk adjustment

Z29.81 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How Z29.81 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to Z29.81.

  • EncounterHIVpre-exposure prophylaxis
  • EncounterHIVPrEP
  • Encounterprophylactic measuresHIV pre-exposure

Related codes at this level

Codes that share Z29.8. If Z29.81 is not quite right, the correct code is usually one of these.

Questions about Z29.81

Is Z29.81 a billable ICD-10-CM code?
Yes. Z29.81 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does Z29.81 sit in the tabular list?
Factors influencing health status and contact with health services (Z00-Z99), in the block Persons with potential health hazards related to communicable diseases (Z20-Z29).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.