MCMedicalCodingSoftware
Z29.81

Z29.81: Encounter for HIV pre-exposure prophylaxis

Billable / specific codeICD-10-CMPOA exempt

Z29.81 is a billable, specific ICD-10-CM code for encounter for hiv pre-exposure prophylaxis. It is valid for submission on a claim.

Check Z29.81 with the rest of the claim: free scrubber

Code also

Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.

  • , if applicable, risk factors for HIV, such as:
  • contact with and (suspected) exposure to human immunodeficiency virus [HIV] (Z20.6)
  • high risk sexual behavior (Z72.5-)

Excludes1 inherited from the categories above Z29.81

A category’s note binds every code beneath it.

Written on Z29: Encounter for other prophylactic measures

  • desensitization to allergens (Z51.6)
  • prophylactic surgery (Z40.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Alphabetic index entries that lead here

  • Encounter›HIV›pre-exposure prophylaxis
  • Encounter›HIV›PrEP
  • Encounter›prophylactic measures›HIV pre-exposure

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under Z29.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.