Is Z22.7 a billable ICD-10-CM code?

Yes. Z22.7 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does Z22.7 sit in the tabular list?

Factors influencing health status and contact with health services (Z00-Z99), in the block Persons with potential health hazards related to communicable diseases (Z20-Z29).

What cannot be coded together with Z22.7?

Z22.7 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter.

Z22.7

Z22.7 — Latent tuberculosis

Billable / specific codeICD-10-CMPOA exempt

Z22.7 is a billable, specific ICD-10-CM code for latent tuberculosis. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis (R76.12)
nonspecific reaction to tuberculin skin test without active tuberculosis (R76.11)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Latent tuberculosis infection (LTBI)

Excludes2 inherited from the categories above Z22.7

Also inherited, and the opposite of Excludes1: these conditions are not part of Z22.7, but a patient can have both, so you may code both.

Written on Z22 — Carrier of infectious disease

carrier of viral hepatitis (B18.-)

Other codes that can never be billed with Z22.7

These codes carry an Excludes1 note pointing at Z22.7. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading Z22.7 alone.

Z20Contact with and (suspected) exposure to communicable diseases
R82.7Abnormal findings on microbiological examination of urine
R83.5Abnormal microbiological findings in cerebrospinal fluid
R84.5Abnormal microbiological findings in specimens from respiratory organs and thorax
R85.5Abnormal microbiological findings in specimens from digestive organs and abdominal cavity
R86.5Abnormal microbiological findings in specimens from male genital organs
R87.5Abnormal microbiological findings in specimens from female genital organs
R89.5Abnormal microbiological findings in specimens from other organs, systems and tissues

Risk adjustment

Z22.7 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

Z22.7 is named in 3 Medicare coverage policies — 3 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A58801Billing and Coding: Pharmacogenomics Testing
A58812Billing and Coding: Pharmacogenomics Testing
A59915Billing and Coding: Pharmacogenomic Testing

How Z22.7 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to Z22.7.

LTBI(latent tuberculosis infection)
Tuberculosis, tubercular, tuberculous›latent
Infection, infected, infective›tuberculous›latent(LTBI)
Tuberculosis, tubercular, tuberculous›abscess›latent

Code history

Z22.7 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share Z22. If Z22.7 is not quite right, the correct code is usually one of these.

Questions about Z22.7

Is Z22.7 a billable ICD-10-CM code?: Yes. Z22.7 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does Z22.7 sit in the tabular list?: Factors influencing health status and contact with health services (Z00-Z99), in the block Persons with potential health hazards related to communicable diseases (Z20-Z29).
What cannot be coded together with Z22.7?: Z22.7 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter.