MCMedicalCodingSoftware
Z22.7

Z22.7: Latent tuberculosis

Billable / specific codeICD-10-CMPOA exempt

Z22.7 is a billable, specific ICD-10-CM code for latent tuberculosis. It is valid for submission on a claim.

Check Z22.7 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis (R76.12)
  • nonspecific reaction to tuberculin skin test without active tuberculosis (R76.11)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Latent tuberculosis infection (LTBI)

Excludes2 inherited from the categories above Z22.7

Not part of this code, but both may be coded when both are present.

Written on Z22: Carrier of infectious disease

  • carrier of viral hepatitis (B18.-)

Other codes that can never be billed with Z22.7

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • Z20Contact with and (suspected) exposure to communicable diseases
  • R82.7Abnormal findings on microbiological examination of urine
  • R83.5Abnormal microbiological findings in cerebrospinal fluid
  • R84.5Abnormal microbiological findings in specimens from respiratory organs and thorax
  • R85.5Abnormal microbiological findings in specimens from digestive organs and abdominal cavity
  • R86.5Abnormal microbiological findings in specimens from male genital organs
  • R87.5Abnormal microbiological findings in specimens from female genital organs
  • R89.5Abnormal microbiological findings in specimens from other organs, systems and tissues

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

Z22.7 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A58801Billing and Coding: Pharmacogenomics Testing
  • A58812Billing and Coding: Pharmacogenomics Testing
  • A59915Billing and Coding: Pharmacogenomic Testing

Alphabetic index entries that lead here

  • LTBI(latent tuberculosis infection)
  • Tuberculosis, tubercular, tuberculous›latent
  • Infection, infected, infective›tuberculous›latent(LTBI)
  • Tuberculosis, tubercular, tuberculous›abscess›latent

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under Z22

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.