Z21: Asymptomatic human immunodeficiency virus [HIV] infection status
Z21 is a billable, specific ICD-10-CM code for asymptomatic human immunodeficiency virus [hiv] infection status. It is valid for submission on a claim.
Check Z21 with the rest of the claim: free scrubberExcludes1: never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
Code first
The underlying condition must be sequenced before this code.
- Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- HIV positive NOS
Other codes that can never be billed with Z21
Their own Excludes1 notes name this code, so the conflict is not listed above.
Risk adjustment
Z21 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 1 HIV/AIDS0.301 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.
Medicare coverage
Z21 is named in 10 Medicare coverage policies: 10 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.
- A55717Billing and Coding: Lab: Flow Cytometry
- A56464Billing and Coding: Flow Cytometry
- A57689Billing and Coding: Lab: Flow Cytometry
- A58710Billing and Coding: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing
Alphabetic index entries that lead here
- HIV›positive, seropositive
- Status›human immunodeficiency virus infection, asymptomatic(HIV)
- Syndrome›retroviral seroconversion(acute)
- Syndrome›seroconversion, retroviral(acute)
- Human›immunodeficiency virus›asymptomatic status
- Test, tests, testing›HIV›positive
- Test, tests, testing›HIV›seropositive
Code history
Unchanged in every release from FY2024 to FY2027.