MCMCB Pro
Z17.420

Z17.420Hormone receptor negative with human epidermal growth factor receptor 2 positive status

Billable / specific codeICD-10-CMPOA exempt

Z17.420 is a billable, specific ICD-10-CM code for hormone receptor negative with human epidermal growth factor receptor 2 positive status. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • HR- with HER2+

Risk adjustment

Z17.420 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How Z17.420 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to Z17.420.

  • Statuscombined receptornegativehormone receptor negative with human epidermal growth factor receptor 2 positive

Related codes at this level

Codes that share Z17.42. If Z17.420 is not quite right, the correct code is usually one of these.

Questions about Z17.420

Is Z17.420 a billable ICD-10-CM code?
Yes. Z17.420 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does Z17.420 sit in the tabular list?
Factors influencing health status and contact with health services (Z00-Z99), in the block Estrogen, and other hormones and factors receptor status (Z17).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.