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T80.49

T80.49: Other Rh incompatibility reaction due to transfusion of blood or blood products

Non-billable headerICD-10-CM

T80.49 is a non-billable header ICD-10-CM code for other rh incompatibility reaction due to transfusion of blood or blood products. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.

This code requires a 7th character

The appropriate 7th character is to be added to each code from category T80

A
initial encounter
D
subsequent encounter
S
sequela

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Delayed serologic transfusion reaction (DSTR) from Rh incompatibility
  • Other reaction to Rh incompatible blood transfusion

Excludes2 inherited from the categories above T80.49

Not part of this code, but both may be coded when both are present.

Written on T80: Complications following infusion, transfusion and therapeutic injection

  • bone marrow transplant rejection (T86.01)
  • febrile nonhemolytic transfusion reaction (R50.84)
  • fluid overload due to transfusion (E87.71)
  • posttransfusion purpura (D69.51)
  • transfusion associated circulatory overload (TACO) (E87.71)
  • transfusion (red blood cell) associated hemochromatosis (E83.111)
  • transfusion related acute lung injury (TRALI) (J95.84)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Alphabetic index entries that lead here

  • Complication›transfusion›incompatibility reaction›Rh›delayed serologic(DSTR)
  • Complication›transfusion›incompatibility reaction›Rh›specified NEC

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead T80.49

3 child codes. Green means billable.

Other codes under T80.4

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.