MCMedicalCodingSoftware
T45

T45: Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified

Non-billable headerICD-10-CM

T45 is a non-billable header ICD-10-CM code for poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.

This code requires a 7th character

The appropriate 7th character is to be added to each code from category T45

A
initial encounter
D
subsequent encounter
S
sequela

Other codes that can never be billed with T45

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • T36Poisoning by, adverse effect of and underdosing of systemic antibiotics
  • T37.5Poisoning by, adverse effect of and underdosing of antiviral drugs
  • T45.1Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugs
  • T45.APoisoning by, adverse effect of and underdosing of immune checkpoint inhibitors and immunostimulant drugs

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead T45

11 child codes. Green means billable.

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.