MCMedicalCodingSoftware
T43.22

T43.22: Poisoning by, adverse effect of and underdosing of selective serotonin reuptake inhibitors

Non-billable headerICD-10-CM

T43.22 is a non-billable header ICD-10-CM code for poisoning by, adverse effect of and underdosing of selective serotonin reuptake inhibitors. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.

This code requires a 7th character

The appropriate 7th character is to be added to each code from category T43

A
initial encounter
D
subsequent encounter
S
sequela

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Poisoning by, adverse effect of and underdosing of SSRI antidepressants

Excludes2 inherited from the categories above T43.22

Not part of this code, but both may be coded when both are present.

Written on T43: Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified

  • appetite depressants (T50.5-)
  • barbiturates (T42.3-)
  • benzodiazepines (T42.4-)
  • drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.- -F19.-)
  • methaqualone (T42.6-)
  • psychodysleptics [hallucinogens] (T40.7-T40.9-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead T43.22

6 child codes. Green means billable.

Other codes under T43.2

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.