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R85.81

R85.81Anal high risk human papillomavirus (HPV) DNA test positive

Billable / specific codeICD-10-CM

R85.81 is a billable, specific ICD-10-CM code for anal high risk human papillomavirus (hpv) dna test positive. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • anogenital warts due to human papillomavirus (HPV) (A63.0)
  • condyloma acuminatum (A63.0)

Risk adjustment

R85.81 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How R85.81 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to R85.81.

  • Abnormal, abnormality, abnormalitiescytologyanushuman papillomavirus DNA testhigh risk positive
  • Abnormal, abnormality, abnormalitiesPapanicolaouanushuman papillomavirus DNA testhigh risk positive

Related codes at this level

Codes that share R85.8. If R85.81 is not quite right, the correct code is usually one of these.

Questions about R85.81

Is R85.81 a billable ICD-10-CM code?
Yes. R85.81 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does R85.81 sit in the tabular list?
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99), in the block Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89).
What cannot be coded together with R85.81?
R85.81 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.