MCMCB Pro
R76.81

R76.81Abnormal rheumatoid factor and anti-citrullinated protein antibody without rheumatoid arthritis

Billable / specific codeICD-10-CM

R76.81 is a billable, specific ICD-10-CM code for abnormal rheumatoid factor and anti-citrullinated protein antibody without rheumatoid arthritis. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • rheumatoid arthritis with rheumatoid factor (M05.-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Abnormal anti-CCP
  • Abnormal anti-cyclic citrullinated protein antibody and rheumatoid factor

Risk adjustment

R76.81 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

R76.81 is named in 2 Medicare coverage policies 2 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A55028Billing and Coding: Lab: Bladder/Urothelial Tumor Markers
  • A56421Billing and Coding: CT of the Abdomen and Pelvis

How R76.81 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to R76.81.

  • Abnormal, abnormality, abnormalitiesanti-CCP(cyclic citrullinated protein)
  • Abnormal, abnormality, abnormalitiesanti-cyclic citrullinated protein antibody and rheumatoid factor
  • Abnormal, abnormality, abnormalitiesrheumatoid factor and anti-citrullinated protein antibodywithout rheumatoid arthritis

Related codes at this level

Codes that share R76.8. If R76.81 is not quite right, the correct code is usually one of these.

Questions about R76.81

Is R76.81 a billable ICD-10-CM code?
Yes. R76.81 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does R76.81 sit in the tabular list?
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99), in the block Abnormal findings on examination of blood, without diagnosis (R70-R79).
What cannot be coded together with R76.81?
R76.81 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.