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R53.0

R53.0: Neoplastic (malignant) related fatigue

Billable / specific codeICD-10-CM

R53.0 is a billable, specific ICD-10-CM code for neoplastic (malignant) related fatigue. It is valid for submission on a claim.

Check R53.0 with the rest of the claim: free scrubber

Code first

The underlying condition must be sequenced before this code.

  • associated neoplasm

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

R53.0 is named in 10 Medicare coverage policies: 10 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A54969Billing and Coding: Nerve Conduction Studies and Electromyography
  • A56619Billing and Coding: Nerve Conduction Studies and Electromyography
  • A57122Billing and Coding: Parathormone (Parathyroid Hormone)
  • A57189Billing and Coding: Serum Magnesium

Alphabetic index entries that lead here

  • Fatigue›neoplasm-related

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under R53

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.