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P91.3

P91.3Neonatal cerebral irritability

Billable / specific codeICD-10-CM

P91.3 is a billable, specific ICD-10-CM code for neonatal cerebral irritability. It is valid for submission on a claim.

Other codes that can never be billed with P91.3

These codes carry an Excludes1 note pointing at P91.3. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading P91.3 alone.

  • P91.6Hypoxic ischemic encephalopathy [HIE]
  • R68.1Nonspecific symptoms peculiar to infancy

Risk adjustment

P91.3 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 202 Coma, Brain Compression/Anoxic Damage0.543 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

P91.3 is named in 1 Medicare coverage policy 1 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A57204Billing and Coding: MRI and CT Scans of the Head and Neck

How P91.3 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to P91.3.

  • Irritable, irritabilitycerebral, in newborn

Related codes at this level

Codes that share P91. If P91.3 is not quite right, the correct code is usually one of these.

Questions about P91.3

Is P91.3 a billable ICD-10-CM code?
Yes. P91.3 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does P91.3 sit in the tabular list?
Certain conditions originating in the perinatal period (P00-P96), in the block Other disorders originating in the perinatal period (P90-P96).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.