MCMedicalCodingSoftware
O29.21

O29.21Cerebral anoxia due to anesthesia during pregnancy

Non-billable headerICD-10-CM

O29.21 is a non-billable header ICD-10-CM code for cerebral anoxia due to anesthesia during pregnancy. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes2 inherited from the categories above O29.21

Also inherited, and the opposite of Excludes1: these conditions are not part of O29.21, but a patient can have both, so you may code both.

Written on O29 Complications of anesthesia during pregnancy

  • complications of anesthesia during labor and delivery (O74.-)
  • complications of anesthesia during the puerperium (O89.-)

Other codes that can never be billed with O29.21

These codes carry an Excludes1 note pointing at O29.21. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading O29.21 alone.

  • T41Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases
  • T88.2Shock due to anesthesia
  • T88.2XXAShock due to anesthesia, initial encounter
  • T88.2XXDShock due to anesthesia, subsequent encounter
  • T88.2XXSShock due to anesthesia, sequela

Risk adjustment

O29.21 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code history

O29.21 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Code to one of these instead O29.21

4 child codes. Green means billable.

Related codes at this level

Codes that share O29.2. If O29.21 is not quite right, the correct code is usually one of these.

Questions about O29.21

Is O29.21 a billable ICD-10-CM code?
No. O29.21 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does O29.21 sit in the tabular list?
Pregnancy, childbirth and the puerperium (O00-O9A), in the block Other maternal disorders predominantly related to pregnancy (O20-O29).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.