MCMedicalCodingSoftware
K21.01

K21.01: Gastro-esophageal reflux disease with esophagitis, with bleeding

Billable / specific codeICD-10-CM

K21.01 is a billable, specific ICD-10-CM code for gastro-esophageal reflux disease with esophagitis, with bleeding. It is valid for submission on a claim.

Check K21.01 with the rest of the claim: free scrubber

Excludes1 inherited from the categories above K21.01

A category’s note binds every code beneath it.

Written on K21: Gastro-esophageal reflux disease

  • newborn esophageal reflux (P78.83)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

K21.01 is named in 15 Medicare coverage policies: 11 listing it as supporting medical necessity, and 4 listing it as NOT covered. Which one applies depends on your Medicare contractor.

  • A59015Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasianot covered
  • A59032Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasianot covered
  • A59051Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasianot covered
  • A59121Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasianot covered

Alphabetic index entries that lead here

  • Esophagitis›due to gastrointestinal reflux disease›with bleeding
  • Esophagitis›reflux›with bleeding
  • Disease, diseased›gastroesophageal reflux›with esophagitis›with bleeding
  • Reflux›esophageal›with esophagitis›with bleeding
  • Reflux›gastroesophageal›with esophagitis›with bleeding
  • Allergy, allergic›milk protein›gastroesophageal reflux›with esophagitis›with bleeding
  • Ulcer, ulcerated, ulcerating, ulceration, ulcerative›esophagus›due to›gastrointestinal reflux disease›with bleeding

The condition this code belongs to

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under K21.0

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.