I25.110 — Atherosclerotic heart disease of native coronary artery with unstable angina pectoris
I25.110 is a billable, specific ICD-10-CM code for atherosclerotic heart disease of native coronary artery with unstable angina pectoris. It is valid for submission on a claim.
Excludes1 — never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
- unstable angina without atherosclerotic heart disease (I20.0)
Excludes2 inherited from the categories above I25.110
Also inherited, and the opposite of Excludes1: these conditions are not part of I25.110, but a patient can have both, so you may code both.
Written on I25.1 — Atherosclerotic heart disease of native coronary artery
Written on I25 — Chronic ischemic heart disease
- non-ischemic myocardial injury (I5A)
Risk adjustment
I25.110 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 229 Unstable Angina and Other Acute Ischemic Heart Disease0.240 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
I25.110 is named in 61 Medicare coverage policies — 61 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A52850Billing and Coding: Cardiac Catheterization and Coronary Angiography
- A52850Billing and Coding: Cardiac Catheterization and Coronary Angiography
- A52992Billing and Coding: Non-Invasive Cerebrovascular Arterial Studies
- A56423Billing and Coding: Cardiology Non-emergent Outpatient Stress Testing
How I25.110 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to I25.110.
- Arteriosclerosis, arteriosclerotic›coronary›native vessel›with›angina pectoris›unstable
Code history
I25.110 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.
Related codes at this level
Codes that share I25.11. If I25.110 is not quite right, the correct code is usually one of these.
- I25.111Atherosclerotic heart disease of native coronary artery with angina pectoris with documented spasm
- I25.112Atherosclerotic heart disease of native coronary artery with refractory angina pectoris
- I25.118Atherosclerotic heart disease of native coronary artery with other forms of angina pectoris
- I25.119Atherosclerotic heart disease of native coronary artery with unspecified angina pectoris
Questions about I25.110
- Is I25.110 a billable ICD-10-CM code?
- Yes. I25.110 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does I25.110 sit in the tabular list?
- Diseases of the circulatory system (I00-I99), in the block Ischemic heart diseases (I20-I25).
- What cannot be coded together with I25.110?
- I25.110 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter.