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H21.81

H21.81: Floppy iris syndrome

Billable / specific codeICD-10-CM

H21.81 is a billable, specific ICD-10-CM code for floppy iris syndrome. It is valid for submission on a claim.

Check H21.81 with the rest of the claim: free scrubber

Use additional code

Add a secondary code to capture the detail described below.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Intraoperative floppy iris syndrome (IFIS)

Excludes2 inherited from the categories above H21.81

Not part of this code, but both may be coded when both are present.

Written on H21: Other disorders of iris and ciliary body

  • sympathetic uveitis (H44.1-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

H21.81 is named in 12 Medicare coverage policies: 12 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A53060Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
  • A56453Billing and Coding: Cataract Extraction
  • A56544Billing and Coding: Cataract Extraction
  • A56615Billing and Coding: Cataract Extraction (including Complex Cataract Surgery)

Alphabetic index entries that lead here

  • Floppy›iris syndrome(intraoperative) (IFIS)
  • Syndrome›floppy›iris(intraoeprative) (IFIS)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under H21.8

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.