F12.21 — Cannabis dependence, in remission
F12.21 is a billable, specific ICD-10-CM code for cannabis dependence, in remission. It is valid for submission on a claim.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Cannabis use disorder, moderate, in early remission
- Cannabis use disorder, moderate, in sustained remission
- Cannabis use disorder, severe, in early remission
- Cannabis use disorder, severe, in sustained remission
Excludes1 inherited from the categories above F12.21
These are not written on F12.21, but they bind it: a note on a category applies to every code beneath it. Billing F12.21 with anything listed here is a denial.
Excludes2 inherited from the categories above F12.21
Also inherited, and the opposite of Excludes1: these conditions are not part of F12.21, but a patient can have both, so you may code both.
Risk adjustment
F12.21 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 137 Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications0.424 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
F12.21 is named in 15 Medicare coverage policies — 12 listing it as supporting medical necessity, and 3 listing it as NOT covered. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A52434Health and Behavior Assessment/Intervention – Medical Policy Articlenot covered
- A56865Billing and Coding: Psychiatric Inpatient Hospitalizationnot covered
- A59718Billing and Coding: Opioid Treatment Programsnot covered
- A54799Billing and Coding: Urine Drug Testing
How F12.21 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to F12.21.
- Dependence›drug NEC›cannabis›in remission
- Disorder›cannabis use›moderate or severe›in remission(early) (sustained)
Code history
F12.21 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.
Related codes at this level
Codes that share F12.2. If F12.21 is not quite right, the correct code is usually one of these.
- F12.20Cannabis dependence, uncomplicated
- F12.22Cannabis dependence with intoxication
- F12.23Cannabis dependence with withdrawal
- F12.25Cannabis dependence with psychotic disorder
- F12.28Cannabis dependence with other cannabis-induced disorder
- F12.29Cannabis dependence with unspecified cannabis-induced disorder
Questions about F12.21
- Is F12.21 a billable ICD-10-CM code?
- Yes. F12.21 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does F12.21 sit in the tabular list?
- Mental, Behavioral and Neurodevelopmental disorders (F01-F99), in the block Mental and behavioral disorders due to psychoactive substance use (F10-F19).
- What cannot be coded together with F12.21?
- F12.21 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above F12.21 (F12.2) and apply to it just the same.