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C91.00

C91.00Acute lymphoblastic leukemia not having achieved remission

Billable / specific codeICD-10-CM

C91.00 is a billable, specific ICD-10-CM code for acute lymphoblastic leukemia not having achieved remission. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Acute lymphoblastic leukemia with failed remission
  • Acute lymphoblastic leukemia NOS

Risk adjustment

C91.00 risk-adjusts. Under the CMS-HCC V28 model it maps to these categories:

  • HCC 18 Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid2.341 RAF
  • HCC 18 Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid2.341 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

C91.00 is named in 80 Medicare coverage policies 80 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52479Oral Anticancer Drugs - Policy Article
  • A52479Oral Anticancer Drugs - Policy Article
  • A52479Oral Anticancer Drugs - Policy Article
  • A52479Oral Anticancer Drugs - Policy Article

Related codes at this level

Codes that share C91.0. If C91.00 is not quite right, the correct code is usually one of these.

Questions about C91.00

Is C91.00 a billable ICD-10-CM code?
Yes. C91.00 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does C91.00 sit in the tabular list?
Neoplasms (C00-D49), in the block Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.